Single Molecule Interaction

Our dream is to unlock dynamic single-molecule analysis. Understanding the root cause of diseases at the molecular level is one of the greatest scientific challenges of today. Expanding the knowledge of biological processes that are at the basis of disease is key for prevention and the development of future cures. We aim to create the best possible tools for researchers to perform high-quality, high-throughput single-molecule experiments in the most accessible manner. With this in mind, we bring to you the a new generation of the Acoustic Force Spectroscopy platform. We are always looking for ways to advance the technology and to bring new features that enable breakthrough discoveries.

"Combining single-molecule mechanical and fluorescence experiments appears to be the most powerful way to unravel the dynamics and structural transactions that occur during complex biomolecular interactions.".

Products

• Lumicks AFS G2 The essence of the AFS™ technology lies in a glass microfluidic chip with a piezo element that generates resonant acoustic waves (ultrasound). These resonant acoustic waves are used to exert forces on micrometer-sized particles with a different density than the surrounding medium — e.g. a polystyrene microsphere or a living cell.
• Lumicks C-Trap With the C-Trap, the correlation of the mechanical and fluorescence measurements is achieved in a controlled and quantitative manner. This enables you to study biological processes at the single-molecule level from multiple angles, providing an unparalleled, wide perspective on biomolecular interactions—quickly and effectively.
• Lumicks M-Trap Using LUMICKS' pioneering m-Trap optical tweezers, scientists of all biological disciplines and backgrounds are able to study and discern the high complexities of molecular processes with base-pair resolution.
• Lumicks U-Flux The u-Flux™ microfluidics system is an integrated solution to reliably perform single-molecule experiments in a laminar flow environment. The stand-alone microfluidics system consists of a laminar flow cell, a highly stable passive pressure system and multiple fluidic valves that can be operated manually or remotely using the automated fluidic valves system.
• Lumicks Z-Movi The z-Movi is an automated, standardized platform to deliver effective screening and sorting of cells based on their interaction with other cells or ligands.